Product Name: ASK 1 Polyclonal Antibody
Catalog No.: ALT0371
Reactivity: Human;Rat;Mouse;
Applications: WB;IHC-p;IF(paraffin section);ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: MAP3K5
Protein Name: Mitogen-activated protein kinase kinase kinase 5
Human Gene ID: 4217
Human Swiss Prot No.: Q99683
Other Name: MAP3K5; ASK1; MAPKKK5; MEKK5; Mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5
Subcellular Location: Cytoplasm . Endoplasmic reticulum. Interaction with 14-3-3 proteins alters the distribution of MAP3K5/ASK1 and restricts it to the perinuclear endoplasmic reticulum region.
Expression: Abundantly expressed in heart and pancreas.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ASK1 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from MDA-MB-435 cells, using ASK1 Antibody. The lane on the right is blocked with the synthesized peptide.
For research use only. Not for use in diagnostic procedures.