Product Name: Arrestin-β-1 (phospho Ser412) Polyclonal Antibody
Catalog No.: ALP0642
Reactivity: Human;Monkey
Applications: WB;IHC-p;IF(paraffin section);ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: ARRB1
Protein Name: Beta-arrestin-1
Human Gene ID: 408
Human Swiss Prot No.: P49407
Other Name: ARRB1; ARR1; Beta-arrestin-1; Arrestin beta-1
Subcellular Location: Cytoplasm. Nucleus. Cell membrane. Membrane, clathrin-coated pit . Cell projection, pseudopodium . Cytoplasmic vesicle. Translocates to the plasma membrane and colocalizes with antagonist-stimulated GPCRs. The monomeric form is predominantly located in the nucleus. The oligomeric form is located in the cytoplasm. Translocates to the nucleus upon stimulation of OPRD1 (By similarity). .
Expression: Brain,Peripheral blood,Uterus,
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Arrestin 1 (Phospho-Ser412) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of lysates from COS7 cells treated with Etoposide 25uM 60′, using Arrestin 1 (Phospho-Ser412) Antibody. The lane on the right is blocked with the phospho peptide.
For research use only. Not for use in diagnostic procedures.