Product Name: Ankyrin B rabbit pAb
Catalog No.: ALT8013
Reactivity: Human; Mouse;Rat
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.24% sodium azide.
Dilution: WB 1:500-2000
Storage Stability: -20°C/1 year
Gene Name: ANK2
Protein Name: Ankyrin B
Human Gene ID: 287
Human Swiss Prot No.: Q01484
Other Name: Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)
Subcellular Location: Cytoplasm, cytoskeleton . Membrane . Cytoplasm, myofibril, sarcomere, M line . Apical cell membrane . Cell membrane . Cell junction, synapse, postsynaptic cell membrane . EaYy endosome . Recycling endosome . Lysosome . Mitochondrion . Cytoplasm, myofibril, sarcomere, Z line . Cell membrane, sarcolemma, T-tubule . Expressed at the apical membrane of airway lung epithelial cells (By similarity). Localized to the plasma membrane of the inner segments of photoreceptors in retina. Colocalizes with SPTBN1 in a distinct intracellular compartment of neonatal cardiomyocytes (PubMed:19007774). In skeletal muscle, localizes to neuromuscular junctions (By similarity). Localizes with puncta at mitochondria ends. Colocalizes and cotransports on motile vesicles with RABGAP1L (By similarity). .
Expression: Present in plasma membrane of neurons as well as glial cells throughout the brain. Expressed in fetal brain and in temporal cortex of adult brain. Also expressed in the inner segments of rod photoreceptors in retina.
For research use only. Not for use in diagnostic procedures.