Product Name: Alix Polyclonal Antibody
Catalog No.: ALT6283
Reactivity: Human;Rat;Mouse;
Applications: WB; ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000, ELISA(peptide)1:5000-20000
Storage Stability: -20°C/1 year
Gene Name: PDCD6IP AIP1 ALIX KIAA1375
Protein Name: Alix
Human Gene ID: 10015
Human Swiss Prot No.: Q8WUM4
Other Name: Programmed cell death 6-interacting protein (PDCD6-interacting protein;ALG-2-interacting protein 1;Hp95)
Subcellular Location: Cytoplasm, cytosol . Melanosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Secreted, extracellular exosome . Cell junction, tight junction . Midbody, Midbody ring . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Colocalized with CEP55 at centrosomes of non-dividing cells. Component of the actomyosin-tight junction complex (By similarity). PDCD6IP targeting to the midbody requires the interaction with CEP55 (PubMed:18641129). .
Expression: Brain,Lymph,Osteosarcoma,Placenta,Testis,
Western blot analysis of lysates from HT-29, NIH/3T3, and HepG2 cells, primary antibody was diluted at 1:1000, 4° over night, secondary antibody(cat: RS23920)was diluted at 1:10000, 37° 1hour.
For research use only. Not for use in diagnostic procedures.