ABCB5 rabbit pAb

Catalog No.: 

Product Name: ABCB5 rabbit pAb

Catalog No.: ALT7794

Reactivity: Human;Rat;Mouse;

Applications: WB; ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Storage Stability: -20°C/1 year

Gene Name: ABCB5

Protein Name: ABCB5

Human Gene ID: 340273

Human Swiss Prot No.: Q2M3G0

Other Name: ATP-binding cassette sub-family B member 5 (ABCB5 P-gp;P-glycoprotein ABCB5)

Subcellular Location: Cell membrane ; Multi-pass membrane protein .

Expression: Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Highly expressed in several malignant tissues: highly expressed in clinical melanomas, with low expression in normal skin. In melanoma, marks malignant melanoma-initiating cells (MMIC), in which clinical virulence resides as a consequence of unlimited self-renewal capacity, resulting in inexorable tumor progression and metastasis. Also highly expressed in a number of leukemia cells. Expressed in basal limbal epithelium.

For research use only. Not for use in diagnostic procedures.

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