Product Name: CD8A rabbit pAb
Catalog No.: ALT7958
Reactivity: Human;Rat;Mouse;
Applications: WB; ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:1000-2000 ELISA 1:5000-20000
Storage Stability: -20°C/1 year
Gene Name: CD8A MAL
Protein Name: CD8A
Human Gene ID: 925
Human Swiss Prot No.: P01732
Other Name: T-cell surface glycoprotein CD8 alpha chain (T-lymphocyte differentiation antigen T8/Leu-2;CD antigen CD8a)
Subcellular Location: [Isoform 1]: Cell membrane ; Single-pass type I membrane protein. CD8A localizes to lipid rafts only when associated with its partner CD8B. .; [Isoform 2]: Secreted .
Expression: CD8 on thymus-derived T-cells usually consists of a disulfide-linked alpha/CD8A and a beta/CD8B chain. Less frequently, CD8 can be expressed as a CD8A homodimer. A subset of natural killer cells, memory T-cells, intraepithelial lymphocytes, monocytes and dendritic cells expresses CD8A homodimers. Expressed at the cell surface of plasmacytoid dendritic cells upon herpes simplex virus-1 stimulation.
For research use only. Not for use in diagnostic procedures.