Product Name: GPR143 Polyclonal Antibody
Catalog No.: ALT1974
Reactivity: Human;Mouse
Applications: IF/ICC;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Immunofluorescence: 1/200 – 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: GPR143
Protein Name: G-protein coupled receptor 143
Human Gene ID: 4935
Human Swiss Prot No.: P51810
Other Name: GPR143; OA1; G-protein coupled receptor 143; Ocular albinism type 1 protein
Subcellular Location: Melanosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein . Distributed throughout the endo-melanosomal system but most of endogenous protein is localized in unpigmented stage II melanosomes. Its expression on the apical cell membrane is sensitive to tyrosine (PubMed:18828673). .
Expression: Expressed at high levels in the retina, including the retinal pigment epithelium (RPE), and in melanocytes. Weak expression is observed in brain and adrenal gland.
Immunofluorescence analysis of LOVO cells, using GPR143 Antibody. The picture on the right is blocked with the synthesized peptide.
For research use only. Not for use in diagnostic procedures.